Laser Therapy and Photobiomodulation Research Studies

Featured Papers

Published in the HSOA Journal of Alternative, Complementary & Integrative Medicine:
TCM4.0: Why Acupuncture and Photobiomodulation Are a Perfect Marriage

Explore the growing range of research studies on laser and photobiomodulation therapies and their uses and effectiveness:

• Biological Effects of Painless Laser Needle Acupuncture
• Cerebral Effects of Noninvasive Laserneedles Measured by Transorbital and Transtemporal Doppler Sonography
• Changes in Heart Rate Variability (HRV) During Low Level Laser-Needle Acupuncture
• Efficacy of Low-Level Laser Therapy in the Management of Neck Pain: A Systematic Review and Meta-Analysis of Randomised Placebo or Active-Treatment Controlled Trials
• Circulation
• Clinical Study of Laserneedle Acupuncture
• Fibromyalgia in Pain Therapy
• The Efficacy of Acupuncture in Chronic Rotator Cuff Tendinitis: Proposal of a Pilot Randomized Controlled Trial
• Infrared Laser Therapy for Ischemic Stroke: A New Treatment Strategy
• Infrared Laser Therapy for Ischemic Stroke: A New Treatment Strategy: Results of the NeuroThera Effectiveness and Safety Trial-1 (NEST-1)
• Results of a 1-Year Clinical Study of the Application of Laser Stimulation of the Acupuncture Points Used for Arthritis, Neuropathy, Intractable Pain, and Pain from Acute Strain and Sprain
• Laser Tendon Regeneration
• Laserneedle Acupuncture: A Critical Review and Recent Results
• Influence of Low Level Laser Radiation on Migration of Stem Cells
• NIR Spectroscopy Explores the Mysteries of Acupuncture
• Low-Level Laser Therapy Applied Transcranially to Rats After Induction of Stroke Significantly Reduces Long-Term Neurological Deficits
• “Needles of Light”: A New Therapeutic Approach
• Study of the Effect of Helium Neon Laser Irradiation of Acupuncture Points to Peripheral Nerve Regeneration
• Transcranial LED Therapy for Cognitive Dysfunction in Chronic, Mild Traumatic Brain Injury: Two Case Reports
• Intravenous and Interstitial Photodynamic Lasertherapy: New Options in Oncology
• Pilot Study of the Clinical Equivalence of Laser Needle to Metal Acupuncture Needle in Treating Musculoskeletal Pain
• Study of the Efficacy of Low Level Laser in Myocardial Perfusion of Patients with Chronic Stable Angina
• The Laserneedle Body Shower
• Transcranial Infrared Laser Therapy Improves Clinical Rating Scores After Embolic Strokes in Rabbits
• Effectiveness and Safety of Transcranial Laser Therapy for Acute Ischemic Stroke

Additional Research References:

Transcranial Photobiomodulation (PBM) Therapy With Laser or LED Studies To Treat CNS Disorders In Humans

Lampl et al., 2007 (Stroke). Transcranial NIR laser therapy to treat acute ischemic stroke, NeuroThera, NEST-1 study
Zivin et al., 2009 (Stroke). Effectiveness and safety, transcranial NIR laser therapy to treat acute ischemic stroke (NEST study)
Schiffer et al., 2009 (Behav Brain Funct). Transcranial, NIR LED treatment for major depression and anxiety
Naeser & Hamblin, 2011 (Editorial, PMLS). Potential for transcranial laser or LED therapy to treat stroke, TBI and neurodegenerative disease
Naeser, Saltmarche et al., 2011 (PMLS): Transcranial LED to improve cognition in TBI and PTSD, with home treatment (2 case reports)
Whelan et al., 2012 (Front. In Bio.). Therapeutic effect of near infrared (NIR) light on Parkinson’s disease models
Nawashiro et al., 2012 (PMLS). Focal increase in cerebral blood flow after transcranial, NIR LED to forehead in severe, chronic TBI (persistent vegetative state)
Gonzalez-Lima et al., 2013 (Neuroscience). Transcranial Infrared Laser Stimulation Produces Beneficial Cognitive and Emotional Effects in Humans
Naeser, Zafonte et al., 2014 (J of Neurotrauma). Significant improvement in cognition post- 18 transcranial LED treatments in chronic, TBI
Saltmarche, Naeser et al., 2017 (PMLS). Significant improvement in cognition in 5 chronic, dementia patients post- 12 weeks, transcranial plus intranasal NIR LED treatments

Laser Acupuncture Research by Margaret Naeser, Ph.D., L.Ac., Dipl.Ac. (NCCAOM):

Naeser, 2000 (Lecture at Rehab Inst. Of Chicago). Acupuncture and Laser Acupuncture to Treat Paralysis in Stroke, Research with Neuroimaging, and When to Refer a Patient
Naeser et al., 1995 (AJA). Laser Acupuncture In the Treatment of Paralysis In Stroke Patients: A CT Scan Lesion Site Study
Naeser, 1997 (JACM). Neurological Rehabilitation: Acupuncture and Laser Acupuncture to Treat Paralysis in Stroke, Other Paralytic Conditions, and Pain in Carpal Tunnel Syndrome
Naeser et al., 2002 (APMR). Carpal Tunnel Syndrome Pain Treated With Low-Level Laser and Microamperes Transcutaneous Electric Nerve Stimulation: A Controlled Study
Naeser et al., 1999 (JACM). Carpal Tunnel Syndrome: Clinical Outcome After Low-Level Laser Acupuncture, Microamps Transcutaneous Electrical Nerve Stimulation, and Other Alternative Therapies – An Open Protocol Study
Naeser et al., 1999 (JACM). Review of Second Congress, World Association for Laser Therapy (WALT) Meeting
Schlager et al., 1998 (BJA). Laser Stimulation of Acupuncture Point P6 Reduces Postoperative Vomiting in Children Undergoing Strabismus Surgery
Neuman et al., 1997 (AAI). Narrow-Band Red Light Phototherapy in Perennial Allergic Rhinitis and Nasal Polyposis
Litscher et al., 2005 (Pabst Science Publishers). Collection of studies in laser acupuncture published in this clinical manual – Laserneedle Acupuncture: Science and Practice
Kahn J, 1985 (JOSPT). Case Reports: Open Wound Management with the HeNe (6328 AU) Cold Laser
Kleinkort et al., 1984 (AJA). Laser Acupuncture: Its Use in Physical Therapy
Walker, 1983 (Neuroscience Letters). Relief Chronic Pain by Low Level Power Laser Irradiation
Yinchun, 1992 (IJCA). Puncture of Quchi with He-Ne Laser in the Treatment of Papular Urticaria
Basford, 1989 (CRPRM). The Clinical and Experimental Status of Low Energy Laser Therapy
Yunkui et al., 1987 (JTCM). A Study of The Treatment Schizophrenia With He-Le Laser Irradiation of Acupoint
Zuoze et al., 1986 (JTCM). Therapeutic Effect of He-Le Laser Irradiation of Point Erman in Schizophrenic Auditory Hallucination – A Clinical Assessment
Guangzhi, 1989 (JTCM). Treatment of Pain Laser Irradiation – A Report of 76 Cases
Shaoqin et al., 1990 (JTCM). Treatment of Allergic Rhinitis With Helium Neon Laser on Acupoints